Will BISSA Shoe cabinet with 3 compartments, white, 19 1/4x11x53 1/8 " fit in an Audi A4 Avant 2022?

The A4 Avant pairs a wide mouth with real height: the opening measures 40⅛″ across and 33½″ tall, so upright boxes pass through without a tilt. The floor gives you 41⅜″ with the rear seats up and 72″ once they fold, a gain of 30¾″, with 39″ between the wheel arches at the tightest point. The lift-over sits at 24¾″ and the floor is only 2″ below it, almost level, so long boxes slide in instead of dropping in. Tall furniture cartons and long flat packs both do well here; extra-wide boxes meet the 39″ pinch first. Slide heavy loads across the sill on a blanket rather than lifting them over.

BISSA ships as a single flat box, 54¼″ × 16¾″ × 3″, and it weighs 45 lb 15 oz. At 3″ thick it slides into gaps a built cabinet never would, so the thickness is not your problem. The length is. At 54¼″ you need a trunk that measures long enough on the floor, or one rear seat folded so the box can run forward between the seats. Most hatchbacks take it with the seats down, and any wagon or SUV swallows it flat. Lift it on edge with two hands, and rest it on a long edge rather than a corner, because 45 lb 15 oz of flat pack lands hard and the corners split first.